@joshua_neadow - At least within FNMS, I cannot think of a way to achieve such a report using the existing Report Builder Wizard. You would need to achieve this outside of FNMS:
1) Go to your Active Inventory view and export the results as Excel
2) Create a Custom Report to find all of the Active Inventory devices where the specific application is installed. Download the results to Excel
3) You then need to join together the 2 reports to find Computer Names from your Active Inventory that are not found in the Software Installation report.