I went to the quicktime website and downloaded the standalone file for 6.5.2. My understanding is that starting with 7.0 Quicktime comes in a MSI whereas prior to that it wasn't a MSI. My problem is, and hopefully you can help with this, that the system partition "C:" is locked down from the users and so is the registry. Average users therefore cannot write to "C:" or the registry.
My current package works fine on a box that hasn't been locked down at all. On a box that is locked down a user can start the program and the player comes up but if they were to try and run a .mov they get "Quicktime player has generated errors and will be closed by windows". It says a log will be generated. Now if an Admin logs on it works fine, and then if a user logs on after an admin it is fine. So my logic says that when you run quicktime the first time "and I don't know if this is with my package setup or quicktime behavior" I believe it is either trying to write something to the registry or write something to the C: drive and if a user is the first person to run quicktime, then quicktime is unable to write that file to the drive or value to the registry. The only thing I had changed in the package was the Folder_SystemFolder_Com which contains the following files: quicktime.qtp, quicktime.cpl, qtplugin.log. I changed the permanent value from yes to no only because I didn't want quicktime.cpl left behind. Did you run into any access problems with users just on first run or are installing it as an admin and then running it once. See we are using Active Directory for distribution therefore a user would more than likely be the person who would run quicktime the first time on any given machine.