Create wrong Registry:
I crete the Key with the Component but i can not se how i han decide which key i want to create
Finaly i saw the etting un the Componenet but when e switch on that it is an X64 Compoonenet i get the eror 5008 even wehn i switch all Components to X64
Dan is correct that the Summary Information Stream's Template Summary setting will also need to be updated in addition to setting the component to 64-bit under the component's settings.
This is all documented in InstallShield HelpNet article Targeting 64-Bit Operating Systems with Basic MSI and InstallScript MSI Installations