Communication will occur bidirectional. When a connection is established, the RN150 will use TCP. A TCP connection uses a "3 Way Handshake." Due to the nature of a TCP 3 Way Handshake, when the connection is made, data will flow outbound and inbound, for the duration of the connection.
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For remote communication with WMI, ports should be open for incoming connections to the computer that the connection is being made to. Incoming ports on the computer that is initiating the connection do not need to be open.