If you're signing the files included in your install, sign them before building the install. If your MSI is not embedded in setup.exe, then you can sign the MSI and setup.exe after the install is built (or using the Postbuild Event). If your MSI is embedded in setup.exe and you need to sign the MSI, then you can use the Precompression Event using Premier or SAB. The path variable will reference the directory which contains the MSI.
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