I'm having an issue with running an installation package on Windows 7 (64 bit). I'm able to add an ODBC 64-bit registry entry in HKEY_LOCAL_MACHINE->SOFTWARE->Wow6432Node->ODBC without an issue. However, I'm adding the identical ODBC settings in the registry for 32-bit HKEY_LOCAL_MACHINE->SOFTWARE->ODBC. I'm receiving no errors/warnings from the InstallShield VS 2010 LE package but the entries are not appearing as expected in the system32 registry. I've tried to export/import the registry tree several times, but the entries just for System32 are not being added by the install package.
You would not be able to create 64 bit Setup in InstallShield Limited Edition.
32-bit programs and 64-bit programs that are running on 64-bit operating System operate in different modes. The registry entries of a 32 bit installer would be redirected to Wow6432node that is HKEY_LOCAL_MACHINE\Software\WOW6432node and 64 bit installer would have their registry entries under HKEY_LOCAL_MACHINE\Software.
Please take a moment and refer the following MSDN article which explains about the Registry in 64 bit Operating System
